Disease: Childhood Myelodysplastic Syndrome
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ZRSR2 Q15696 zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2 Nucleic acid binding 1.00 0.751 0.231
U2AF1 P0DN76 Q01081 U2 small nuclear RNA auxiliary factor 1 Nucleic acid binding 0.99 0.604 0.577
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808
SRSF2 Q01130 serine and arginine rich splicing factor 2 Nucleic acid binding 0.48 0.561 0.731
SF3B1 O75533 splicing factor 3b subunit 1 Nucleic acid binding 1.00 0.511 0.731
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
PLCB1 Q9NQ66 phospholipase C beta 1 Enzyme 0.98 0.595 0.654
NPM1 P06748 nucleophosmin 1 Chaperone 1.00 0.464 0.846
LYL1 P12980 LYL1 basic helix-loop-helix family member Transcription factor 0.77 0.670 0.192
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
HFE Q30201 homeostatic iron regulator 2.6E-08 0.436 0.846
GATA2 P23769 GATA binding protein 2 0.98 0.496 0.654
GATA1 P15976 GATA binding protein 1 0.95 0.483 0.808
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885
EPO P01588 erythropoietin 1.1E-02 0.381 0.885
EGR1 P18146 early growth response 1 Nucleic acid binding 0.35 0.433 0.923
DLK1 P80370 delta like non-canonical Notch ligand 1 Signaling 3.5E-02 0.527 0.692
DAPK1 P53355 death associated protein kinase 1 Kinase 1.00 0.472 0.808
CTNNA1 P35221 catenin alpha 1 Cellular structure 0.97 0.584 0.538
CREBBP Q92793 CREB binding protein 1.00 0.428 0.808
CFLAR O15519 CASP8 and FADD like apoptosis regulator Enzyme 1.00 0.485 0.846
CDKN2B P42772 cyclin dependent kinase inhibitor 2B 7.3E-03 0.417 0.769
BMI1 P35226 BMI1 proto-oncogene, polycomb ring finger 0.94 0.448 0.808
ATRX P46100 ATRX chromatin remodeler 1.00 0.452 0.808